Roles of the tumor suppressor inhibitor of growth family member 4 (ING4) in cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in cancer research"
DOI: 10.1016/bs.acr.2021.05.004
Abstract: Inhibitor of growth family member 4 (ING4) is best known as a tumor suppressor that is frequently downregulated, deleted, or mutated in many cancers. ING4 regulates a broad array of tumor-related processes including proliferation, apoptosis,… read more here.
Keywords: member ing4; family member; cancer; inhibitor growth ... See more keywords
Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab1070
Abstract: Abstract Endogenous retroviruses (ERVs) are subject to transcriptional repression in adult tissues, in part to prevent autoimmune responses. However, little is known about the epigenetic silencing of ERV expression. Here, we describe a new role… read more here.
Keywords: growth protein; innate immune; protein epigenetically; inhibitor growth ... See more keywords
Hepatoma Cell-Targeted Cationized Silk Fibroin as a Carrier for the Inhibitor of Growth 4-Interleukin-24 Double Gene Plasmid.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2019.2778
Abstract: The construction of a targeted gene delivery system with low cytotoxicity to normal tissues is an urgent need for the clinical treatment of liver cancer. In this study, Antheraea pernyi silk fibroin (ASF) was cationized… read more here.
Keywords: silk fibroin; gene; hepatoma; inhibitor growth ... See more keywords
Inhibitor of Growth Factors Regulate Cellular Senescence
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14133107
Abstract: Simple Summary Five members of the Inhibitor of Growth (ING) family share a highly conserved plant homeodomian with affinity to the specific histone modification H3K4me3. Since some ING family members are preferentially associated with histone… read more here.
Keywords: inhibitor growth; senescence; cellular senescence; ing family ... See more keywords
MicroRNA-650 targets inhibitor of growth 4 to promote colorectal cancer progression via mitogen activated protein kinase signaling
Sign Up to like & getrecommendations! Published in 2018 at "Oncology Letters"
DOI: 10.3892/ol.2018.8910
Abstract: Colorectal cancer (CRC) is the third most common malignant disease globally and causes numerous cancer-associated mortalities; however, the underlying molecular mechanisms remain unresolved. MicroRNAs (miRs) are endogenous noncoding RNAs that regulate post-transcriptional gene silencing by… read more here.
Keywords: mir 650; colorectal cancer; crc; cancer ... See more keywords