EZH2 Inhibitor GSK126 Suppresses Antitumor Immunity by Driving Production of Myeloid-Derived Suppressor Cells.
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DOI: 10.1158/0008-5472.can-18-2395
Abstract: Enhancer of zeste homolog (EZH2) is a key epigenetic regulator of gene expression and is frequently overexpressed in various cancer types, suggesting a role in oncogenesis. The therapeutic potential of EZH2 inhibitors is currently being… read more here.
Keywords: antitumor immunity; gsk126; ezh2 inhibitor; inhibitor gsk126 ... See more keywords