Amentoflavone is a potent broad-spectrum inhibitor of human UDP-glucuronosyltransferases.
Sign Up to like & getrecommendations! Published in 2018 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2018.02.009
Abstract: Amentoflavone (AMF), an abundant natural biflavonoid found in many medicinal plants, displays various beneficial effects including anti-inflammatory, anti-oxidative and anti-cancer. Despite the extensive studies on pharmacological activities, the toxicity or undesirable effects of AMF are… read more here.
Keywords: inhibitor; inhibitor human; udp glucuronosyltransferases; inhibition ... See more keywords
Potent Inhibitor of Human Trypsins from the Aeruginosin Family of Natural Products.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical biology"
DOI: 10.1021/acschembio.1c00611
Abstract: Serine proteases regulate many physiological processes and play a key role in a variety of cancers. Aeruginosins are a family of natural products produced by cyanobacteria that exhibit pronounced structural diversity and potent serine protease… read more here.
Keywords: potent inhibitor; inhibitor human; family natural; natural products ... See more keywords