Cheminformatics Analysis of Dynamic WNK‐Inhibitor Interactions
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DOI: 10.1002/minf.201700138
Abstract: The With‐No‐Lysine (WNK) serine/threonine kinase family constitutes a unique and distinctive branch of the kinome. The four proteins of this family (WNK1/2/3/4) are involved in blood pressure regulation, body fluid, and electrolyte homeostasis. Herein, we… read more here.
Keywords: wnk inhibitor; dynamic wnk; family; inhibitor interactions ... See more keywords
Rebuttal to Response to the Article “Enzyme–Inhibitor Interactions and a Simple, Rapid Method for Determining Inhibition Modality”
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DOI: 10.1177/2472555219875106
Abstract: The commentary by Dr. Walsh offers a depth of mathematical precision that is to be applauded. We congratulate him on this alternative mathematical treatment of enzyme– inhibitor interactions. At the same time, there is value… read more here.
Keywords: inhibitor; inhibition; enzyme inhibitor; inhibitor interactions ... See more keywords