WP1066, a small molecule inhibitor of the JAK/STAT3 pathway, inhibits ceramide glucosyltransferase activity.
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DOI: 10.1016/j.bbrc.2017.07.115
Abstract: WP1066 is a well-known inhibitor of the JAK/STAT3 signaling pathway. By a screen of known small molecule inhibitors of various enzymes and protein factors, we identified WP1066 as a ceramide glucosyltransferase inhibitor. Ceramide glucosyltransferase catalyzes… read more here.
Keywords: glucosyltransferase; jak stat3; ceramide glucosyltransferase; inhibitor jak ... See more keywords