HDAC2/3 inhibitor MI192 mitigates oligodendrocyte loss and reduces microglial activation upon injury: A potential role of epigenetics
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DOI: 10.5455/ovj.2021.v11.i3.18
Abstract: Background: During development, oligodendrocyte (OL) lineage cells are susceptible to injury, leading to life-long clinical neurodevelopmental deficits, which lack effective treatments. Drugs targeting epigenetic modifications that inhibit histone deacetylases (HDACs) protect from many clinical neurodegenerative… read more here.
Keywords: microglial activation; inhibitor mi192; hdac2 inhibitor; pathology ... See more keywords