New microtubulin inhibitor MT189 suppresses angiogenesis via the JNK-VEGF/VEGFR2 signaling axis.
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DOI: 10.1016/j.canlet.2017.12.022
Abstract: The microtubulin inhibitor MT189 possesses anticancer activity and has been shown to overcome multidrug resistance. Here, we report that MT189 also inhibits angiogenesis. MT189 inhibited the proliferation, migration and differentiation of endothelial cells, with or… read more here.
Keywords: via jnk; inhibitor mt189; jnk; microtubulin inhibitor ... See more keywords