A suicide inhibitor of nematode trehalose-6-phosphate phosphatases
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DOI: 10.1038/s41598-019-52593-9
Abstract: Protein-based drug discovery strategies have the distinct advantage of providing insights into the molecular mechanisms of chemical effectors. Currently, there are no known trehalose-6-phosphate phosphatase (TPP) inhibitors that possess reasonable inhibition constants and chemical scaffolds… read more here.
Keywords: suicide inhibitor; inhibitor; nematode; trehalose phosphate ... See more keywords