Articles with "inhibitor op449" as a keyword



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PPP2CA Is a Novel Therapeutic Target in Neuroblastoma Cells That Can Be Activated by the SET Inhibitor OP449

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.744984

Abstract: Neuroblastoma (NB) is the most common extracranial solid tumor in childhood and has a poor prognosis in high-risk cases, requiring novel therapies. Pathways that depend on phospho-signaling maintain the aggressiveness of NB. Protein phosphatase 2… read more here.

Keywords: inhibitor op449; novel therapeutic; set inhibitor; inhibitor ... See more keywords