Protoporphyrin IX is a dual inhibitor of p53/MDM2 and p53/MDM4 interactions and induces apoptosis in B-cell chronic lymphocytic leukemia cells
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DOI: 10.1038/s41420-019-0157-7
Abstract: Abstractp53 is a tumor suppressor, which belongs to the p53 family of proteins. The family consists of p53, p63 and p73 proteins, which share similar structure and function. Activation of wild-type p53 or TAp73 in… read more here.
Keywords: mdm4 interactions; dual inhibitor; inhibitor p53; p53 ... See more keywords