Design, Characterization, and Biopharmaceutical Behavior of Nanoparticles Loaded with an HIV-1 Fusion Inhibitor Peptide.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b00609
Abstract: New therapeutic alternatives to fight against the spread of HIV-1 are based on peptides designed to inhibit the early steps of HIV-1 fusion in target cells. However, drawbacks, such as bioavailability, short half-life, rapid clearance,… read more here.
Keywords: inhibitor peptide; hiv fusion; fusion inhibitor; fusion ... See more keywords
The Kinase Specificity of Protein Kinase Inhibitor Peptide
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DOI: 10.3389/fphar.2021.632815
Abstract: G-protein-coupled-receptor (GPCR) signaling is exquisitely controlled to achieve spatial and temporal specificity. The endogenous protein kinase inhibitor peptide (PKI) confines the spatial and temporal spread of the activity of protein kinase A (PKA), which integrates… read more here.
Keywords: kinase inhibitor; kinase; inhibitor peptide; protein kinase ... See more keywords