Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3
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DOI: 10.1021/acschembio.2c00299
Abstract: The cancerous inhibitor of protein phosphatase 2A (CIP2A) is an oncoprotein found overexpressed in many types of cancer. CIP2A has been shown to stabilize oncoproteins such as cMYC by shielding them from PP2A-mediated dephosphorylation. Here… read more here.
Keywords: cancerous inhibitor; interaction; inhibitor protein; protein phosphatase ... See more keywords