Novel porcupine (PORCN) inhibitor RXC004: Evaluation in models of RNF43 loss of function cancers.
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DOI: 10.1200/jco.2017.35.15_suppl.e14094
Abstract: e14094Background: Wnt signalling initiates oncogenic pathways involved in tumour initiation, growth, differentiation and metastasis.1 Targeting the Wnt pathway is an attractive approach to cancer t... read more here.
Keywords: evaluation models; rxc004 evaluation; novel porcupine; inhibitor rxc004 ... See more keywords