Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats
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DOI: 10.3389/fcimb.2022.818391
Abstract: Background Neutrophil elastase (NE) is associated with sepsis occurrence and progression. We hypothesized that the NE inhibitor Sivelestat might modulate abnormal gut microbiota and metabolites during sepsis. Methods Sixty Sprague-Dawley (SD) rats were randomly divided… read more here.
Keywords: gut microbiome; inhibitor sivelestat; septic rats; sivelestat ... See more keywords