Effects of fatty acid amide hydrolase inhibitor URB597 in a rat model of trauma-induced long-term anxiety
Sign Up to like & getrecommendations! Published in 2018 at "Psychopharmacology"
DOI: 10.1007/s00213-018-5020-7
Abstract: RationaleThe endocannabinoid neurotransmitter, anandamide, has been implicated in the central modulation of stress responses. Previous animal experiments have shown that inhibitors of the anandamide-degrading enzyme, fatty acid amide hydrolase (FAAH), enhance the ability to cope… read more here.
Keywords: acid amide; anxiety; fatty acid; amide hydrolase ... See more keywords
The fatty-acid amide hydrolase inhibitor URB597 inhibits MICA/B shedding
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DOI: 10.1038/s41598-020-72688-y
Abstract: MICA/B proteins are expressed on the surface of various types of stressed cells, including cancer cells. Cytotoxic lymphocytes expressing natural killer group 2D (NKG2D) receptor recognize MICA/B and eliminate the cells. However, cancer cells evade… read more here.
Keywords: mica; acid amide; inhibitor; fatty acid ... See more keywords
Neuroprotective Effects of VEGF-A Nanofiber Membrane and FAAH Inhibitor URB597 Against Oxygen–Glucose Deprivation-Induced Ischemic Neuronal Injury
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DOI: 10.2147/ijn.s307335
Abstract: Introduction Brain ischemia is a common neurological disorder worldwide that activates a cascade of pathophysiological events involving decreases in oxygen and glucose levels. Despite substantial efforts to explore its pathogenesis, the management of ischemic neuronal… read more here.
Keywords: oxygen glucose; faah inhibitor; membrane; inhibitor urb597 ... See more keywords
Effect of Fatty Acid Amide Hydrolase Inhibitor URB597 on Orofacial Pain Perception in Rats
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DOI: 10.3390/ijms23094665
Abstract: Endocannabinoids act as analgesic agents in a number of headache models. However, their effectiveness varies with the route of administration and the type of pain. In this study, we assessed the role of the fatty… read more here.
Keywords: orofacial pain; inhibitor urb597; acid amide; pain ... See more keywords