Articles with "inhibitor vsig" as a keyword



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A small molecule inhibitor of VSIG-8 prevents its binding to VISTA

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Published in 2022 at "Investigational New Drugs"

DOI: 10.1007/s10637-022-01244-4

Abstract: The V-region immunoglobulin-containing suppressor of T cell activation (VISTA), a unique B7 family member, is an attractive immunotherapeutic target for cancer, autoimmune and inflammatory diseases. In 2016, a patent demonstrated V-Set and Immunoglobulin domain containing… read more here.

Keywords: vsig; small molecule; inhibitor vsig; vista ... See more keywords