Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9
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DOI: 10.1177/2472555218809904
Abstract: Eleven-nineteen leukemia (ENL) contains an epigenetic reader domain (YEATS domain) that recognizes lysine acylation on histone 3 and facilitates transcription initiation and elongation through its interactions with the super elongation complex (SEC) and the histone… read more here.
Keywords: selective inhibitor; yeats domain; inhibitor; discovery selective ... See more keywords