Articles with "inhibitors arylureido" as a keyword



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Discovery of Potent EGFR Inhibitors With 6-Arylureido-4-anilinoquinazoline Derivatives

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Published in 2021 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2021.647591

Abstract: According to the classical pharmacophore fusion strategy, a series of 6-arylureido-4-anilinoquinazoline derivatives ( Compounds 7a – t ) were designed, synthesized, and biologically evaluated by the standard CCK-8 method and enzyme inhibition assay. Among the… read more here.

Keywords: potent egfr; discovery potent; inhibitors arylureido; egfr inhibitors ... See more keywords