Articles with "inhibitors bont" as a keyword



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Identification of Slow-Binding Inhibitors of the BoNT/A Protease.

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Published in 2022 at "ACS medicinal chemistry letters"

DOI: 10.1021/acsmedchemlett.2c00028

Abstract: Botulinum neurotoxin A (BoNT/A) is a lethal toxin, which causes botulism, and is categorized as a bioterrorism threat, which causes flaccid paralysis and death. Botulinum A neurotoxicity is governed through its light chain (LC), a… read more here.

Keywords: binding; identification slow; bont protease; binding inhibitors ... See more keywords