BACE1 inhibitors: Current status and future directions in treating Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2019 at "Medicinal Research Reviews"
DOI: 10.1002/med.21622
Abstract: Alzheimer's disease (AD) is an irreversible, progressive neurodegenerative brain disorder with no current cure. One of the important therapeutic approaches of AD is the inhibition of β‐site APP cleaving enzyme‐1 (BACE1), which is involved in… read more here.
Keywords: bace1 inhibitors; alzheimer disease; treating alzheimer; inhibitors current ... See more keywords
Design and Development of COX-II Inhibitors: Current Scenario and Future Perspective
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.3c00692
Abstract: Innate inflammation beyond a threshold is a significant problem involved in cardiovascular diseases, cancer, and many other chronic conditions. Cyclooxygenase (COX) enzymes are key inflammatory markers as they catalyze prostaglandins production and are crucial for… read more here.
Keywords: inhibitors current; design development; cox inhibitors; cox ... See more keywords