Identification and Optimization of 4‐Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase
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DOI: 10.1002/cmdc.201700663
Abstract: 4‐Anilinoquinolines were identified as potent and narrow‐spectrum inhibitors of the cyclin G associated kinase (GAK), an important regulator of viral and bacterial entry into host cells. Optimization of the 4‐anilino group and the 6,7‐quinoline substituents produced… read more here.
Keywords: associated kinase; kinase; identification optimization; cyclin associated ... See more keywords