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Published in 2020 at "Journal of Medicinal Chemistry"
DOI: 10.2210/pdb6p4v/pdb
Abstract: Deoxyhypusine synthase (DHPS) utilizes spermidine and NAD as cofactors to incorporate a hypusine modification into the eukaryotic translation initiation factor 5A (eIF5A). Hypusine is essential for...
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Keywords:
discovery novel;
novel allosteric;
inhibitors deoxyhypusine;
allosteric inhibitors ... See more keywords