Articles with "inhibitors deoxyhypusine" as a keyword



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Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase

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Published in 2020 at "Journal of Medicinal Chemistry"

DOI: 10.2210/pdb6p4v/pdb

Abstract: Deoxyhypusine synthase (DHPS) utilizes spermidine and NAD as cofactors to incorporate a hypusine modification into the eukaryotic translation initiation factor 5A (eIF5A). Hypusine is essential for... read more here.

Keywords: discovery novel; novel allosteric; inhibitors deoxyhypusine; allosteric inhibitors ... See more keywords