Discovery of potent IDO1 inhibitors derived from tryptophan using scaffold-hopping and structure-based design approaches.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.06.039
Abstract: Indoleamine 2,3-dioxygenase 1 (IDO1) is frequently hijacked by tumors to escape the host immune response, and the enzyme is now firmly established as an attractive target for cancer immunotherapy. To identify novel IDO1 inhibitors suitable… read more here.
Keywords: discovery potent; scaffold hopping; potent ido1; ido1 inhibitors ... See more keywords
Aqueous phase environmental friendly organic corrosion inhibitors derived from one step multicomponent reactions: A review
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2018.11.040
Abstract: Abstract Use of organic compounds as corrosion inhibitors is one of the most profitable, effective and ease methods because of their simplicity and cost-effective synthesis using commercially available inexpensive starting materials. Nowadays, the synthesis of… read more here.
Keywords: inhibitors derived; environmental friendly; aqueous phase; corrosion ... See more keywords
Nicotinic acetylcholine receptor inhibitors derived from snake and snail venoms
Sign Up to like & getrecommendations! Published in 2017 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2017.06.011
Abstract: The nicotinic acetylcholine receptor (nAChR) represents the prototype of ligand-gated ion channels. It is vital for neuromuscular transmission and an important regulator of neurotransmission. A variety of toxic compounds derived from diverse species target this… read more here.
Keywords: receptor inhibitors; nicotinic acetylcholine; receptor; acetylcholine receptor ... See more keywords