JAK inhibitors in dermatology: The promise of a new drug class
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DOI: 10.1016/j.jaad.2016.12.005
Abstract: &NA; New molecularly targeted therapeutics are changing dermatologic therapy. Janus kinase–signal transducer and activator of transcription (JAK‐STAT) is an intracellular signaling pathway upon which many different proinflammatory signaling pathways converge. Numerous inflammatory dermatoses are driven… read more here.
Keywords: dermatology; class; inhibitors dermatology; dermatology promise ... See more keywords
Janus kinase inhibitors in dermatology: Part II. A comprehensive review
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DOI: 10.1016/j.jaad.2021.06.873
Abstract: The Janus kinase-signal transducer and activator of transcription (JAK-STAT) intracellular signaling pathway is implicated in the pathogenesis of a number of inflammatory dermatoses. Clinical trials and other studies have demonstrated the efficacy of JAK inhibitors… read more here.
Keywords: kinase inhibitors; dermatology; inhibitors dermatology; janus kinase ... See more keywords