Chemical Reactivity and Optical and Pharmacokinetics Studies of 14 Multikinase Inhibitors and Their Docking Interactions Toward ACK1 for Precision Oncology
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DOI: 10.3389/fchem.2022.843642
Abstract: Activated Cdc42-associated kinase 1 (ACK1/TNK2) has a significant role in cell endocytosis, survival, proliferation, and migration. Mutations in ACK1 are closely associated with the occurrence and development of cancers. In this work, a conceptual density… read more here.
Keywords: oncology; inhibitors docking; multikinase inhibitors; chemical reactivity ... See more keywords