Overview of Research into mTOR Inhibitors
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DOI: 10.3390/molecules27165295
Abstract: The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that belongs to the phosphoinositide 3-kinase (PI3K)-related kinase (PIKK) family. The kinase exists in the forms of two complexes, mTORC1 and mTORC2, and it participates… read more here.
Keywords: mtor inhibitors; inhibitors dual; kinase; overview research ... See more keywords
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment
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DOI: 10.3390/molecules28073047
Abstract: Despite the significant outcomes attained by scientific research, breast cancer (BC) still represents the second leading cause of death in women. Estrogen receptor-positive (ER+) BC accounts for the majority of diagnosed BCs, highlighting the disruption… read more here.
Keywords: switching aromatase; aromatase inhibitors; inhibitors dual; breast cancer ... See more keywords