Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase.
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DOI: 10.1021/acsmedchemlett.8b00424
Abstract: Endothelial lipase (EL) selectively metabolizes high density lipoprotein (HDL) particles. Inhibition of EL has been shown to increase HDL concentration in preclinical animal models and was targeted as a potential treatment of atherosclerosis. We describe… read more here.
Keywords: inhibitors endothelial; endothelial lipase; hdl; sulfonylated benzothiazoles ... See more keywords