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New Hybrid Tetrahydropyrrolo[3,2,1-ij]quinolin-1-ylidene-2-thioxothiazolidin-4-ones as New Inhibitors of Factor Xa and Factor XIa: Design, Synthesis, and In Silico and Experimental Evaluation

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28093851

Abstract: Despite extensive research in the field of thrombotic diseases, the prevention of blood clots remains an important area of study. Therefore, the development of new anticoagulant drugs with better therapeutic profiles and fewer side effects… read more here.

Keywords: evaluation; new hybrid; synthesis; inhibitors factor ... See more keywords