Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B
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DOI: 10.3390/molecules24091739
Abstract: Background: KDM5 enzymes are H3K4 specific histone demethylases involved in transcriptional regulation and DNA repair. These proteins are overexpressed in different kinds of cancer, including breast, prostate and bladder carcinomas, with positive effects on cancer… read more here.
Keywords: histone demethylases; breast; breast cancer; inhibitors kdm5 ... See more keywords