Small Molecule Inhibitors of Lymphocyte Perforin as Focused Immunosuppressants for Infection and Autoimmunity
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DOI: 10.1021/acs.jmedchem.2c01338
Abstract: New drugs that precisely target the immune mechanisms critical for cytotoxic T lymphocyte (CTL) and natural killer (NK) cell driven pathologies are desperately needed. In this perspective, we explore the cytolytic protein perforin as a… read more here.
Keywords: molecule inhibitors; small molecule; inhibitors lymphocyte; perforin ... See more keywords