Selective protection of human cardiomyocytes from anthracycline cardiotoxicity by small molecule inhibitors of MAP4K4
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DOI: 10.1038/s41598-020-68907-1
Abstract: Given the poor track record to date of animal models for creating cardioprotective drugs, human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have been proposed as a therapeutically relevant human platform to guide target validation and cardiac… read more here.
Keywords: protection; inhibitors map4k4; cell death; kinase kinase ... See more keywords