SGLT2 Inhibitors and Mechanisms of Hypertension
Sign Up to like & getrecommendations! Published in 2018 at "Current Cardiology Reports"
DOI: 10.1007/s11886-018-0943-5
Abstract: Purpose of ReviewWe sought to review currently available data on the safety and efficacy of sodium-glucose cotransporter 2 (SGLT2) inhibitors in type 2 diabetes mellitus patients with hypertension.Recent FindingsInhibition of SGLT2 in the renal proximal… read more here.
Keywords: sglt2 inhibitors; inhibitors mechanisms; cardiology; type diabetes ... See more keywords
Human sirtuin 2 inhibitors, their mechanisms and binding modes.
Sign Up to like & getrecommendations! Published in 2023 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2022-0253
Abstract: The silent information regulator (sirtuin) is a family of enzymes involved in epigenetic processes with lysine deacetylase activity, having as substrates histones and other proteins. They participate in a wide range of cellular and pathologic… read more here.
Keywords: modes human; human sirtuin; mechanisms binding; inhibitors mechanisms ... See more keywords