Articles with "inhibitors mechanistic" as a keyword



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Hemophilia a patients with inhibitors: Mechanistic insights and novel therapeutic implications

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1019275

Abstract: The development of coagulation factor VIII (FVIII) inhibitory antibodies is a serious complication in hemophilia A (HA) patients after FVIII replacement therapy. Inhibitors render regular prophylaxis ineffective and increase the risk of morbidity and mortality.… read more here.

Keywords: hemophilia patients; inhibitors mechanistic; novel therapeutic; insights novel ... See more keywords