Genomic correlates of response to PD-1 axis inhibitors (IO) in metastatic urothelial cancer (mUC) using explainable artificial intelligence (AI).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.6_suppl.570
Abstract: 570Background: AI is increasingly being used in clinical cancer genomics research. Probabilistic Graphical Models (PGMs) are AI algorithms that capture multivariate, mutli-level dependencies in com... read more here.
Keywords: genomic correlates; axis inhibitors; inhibitors metastatic; cancer ... See more keywords
PARP inhibitors in metastatic prostate cancer
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1159557
Abstract: Poly-ADP ribose polymerase inhibitors (PARPi) are an emerging therapeutic option for the treatment of prostate cancer. Their primary mechanism of action is via induction of synthetic lethality in cells with underlying deficiencies in homologous recombination… read more here.
Keywords: prostate cancer; prostate; metastatic prostate; inhibitors metastatic ... See more keywords