Further investigation of inhibitors of MRSA pyruvate kinase: Towards the conception of novel antimicrobial agents.
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DOI: 10.1016/j.ejmech.2016.09.018
Abstract: Several novel series of compounds were synthesized and evaluated as inhibitors of methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase (PK). PK has been identified as a highly interconnected essential 'hub' protein in MRSA, with structural features… read more here.
Keywords: novel antimicrobial; pyruvate kinase; inhibitors mrsa; investigation inhibitors ... See more keywords