microRNA inhibitors: Natural and artificial sequestration of microRNA.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.05.025
Abstract: MicroRNA (miRNAs) is post-transcriptional regulator of mRNA. However, the prevalence and activity of miRNA are regulated by other regulators. miRNA inhibitors are natural or artificial RNA transcripts that sequestrate miRNAs and decrease or even eliminate… read more here.
Keywords: mirna; mirna inhibitors; inhibitors natural; microrna inhibitors ... See more keywords
The roles of glycolysis in osteosarcoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.950886
Abstract: Metabolic reprogramming is of great significance in the progression of various cancers and is critical for cancer progression, diagnosis, and treatment. Cellular metabolic pathways mainly include glycolysis, fat metabolism, glutamine decomposition, and oxidative phosphorylation. In… read more here.
Keywords: natural products; progression; glycolysis osteosarcoma; glycolysis ... See more keywords
Identification of CDK7 Inhibitors from Natural Sources Using Pharmacoinformatics and Molecular Dynamics Simulations
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DOI: 10.3390/biomedicines9091197
Abstract: The cyclin-dependent kinase 7 (CDK7) plays a crucial role in regulating the cell cycle and RNA polymerase-based transcription. Overexpression of this kinase is linked with various cancers in humans due to its dual involvement in… read more here.
Keywords: identification cdk7; cdk7; molecular dynamics; cdk7 inhibitors ... See more keywords
Telomerase Inhibitors from Natural Products and Their Anticancer Potential
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DOI: 10.3390/ijms19010013
Abstract: Telomeres and telomerase are nowadays exploring traits on targets for anticancer therapy. Telomerase is a unique reverse transcriptase enzyme, considered as a primary factor in almost all cancer cells, which is mainly responsible to regulate… read more here.
Keywords: telomerase; natural products; telomerase inhibitors; inhibitors natural ... See more keywords
Identifying HSV-1 Inhibitors from Natural Compounds via Virtual Screening Targeting Surface Glycoprotein D
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15030361
Abstract: Herpes simplex virus (HSV) infections are a worldwide health problem in need of new effective treatments. Of particular interest is the identification of antiviral agents that act via different mechanisms compared to current drugs, as… read more here.
Keywords: compounds via; natural compounds; hsv inhibitors; identifying hsv ... See more keywords