Discovery of potent 4-aminoquinoline hydrazone inhibitors of NRH:quinoneoxidoreductase-2 (NQO2).
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DOI: 10.1016/j.ejmech.2019.111649
Abstract: (NRH):quinone oxidoreductase 2 (NQO2) is associated with various processes involved in cancer initiation and progression probably via the production of ROS during quinone metabolism. Thus, there is a need to develop inhibitors of NQO2 that… read more here.
Keywords: discovery potent; inhibitors nqo2; aminoquinoline; hydrazone ... See more keywords