Gallotannins are uncompetitive inhibitors of pancreatic lipase activity.
Sign Up to like & getrecommendations! Published in 2020 at "Biophysical chemistry"
DOI: 10.1016/j.bpc.2020.106409
Abstract: Inhibition of pancreatic lipase (PL) is used to treat dyslipidemias and obesity. Phenolic compounds are highly bioactive molecules that can inhibit various enzymes. Our aim was to evaluate the inhibitory activity of selected phenolic compounds… read more here.
Keywords: gallotannins uncompetitive; pancreatic lipase; activity; inhibitors pancreatic ... See more keywords
PARP inhibitors in pancreatic cancer: molecular mechanisms and clinical applications
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Cancer"
DOI: 10.1186/s12943-020-01167-9
Abstract: Pancreatic cancer is a highly lethal disease with a poor prognosis, and existing therapies offer only limited effectiveness. Mutation gene sequencing has shown several gene associations that may account for its carcinogenesis, revealing a promising… read more here.
Keywords: parp inhibitors; inhibitors pancreatic; pancreatic cancer; clinical applications ... See more keywords