Cholinesterase and carboxylesterase inhibitors as pharmacological agents
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DOI: 10.1007/s11172-019-2507-2
Abstract: Literature data and authors’ own results on the role of serine hydrolases, acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), as drug targets for treatment of neurodegenerative diseases and carboxylesterase (CaE) inhibitors as modulators of CaE-hydrolysis of ester-containing… read more here.
Keywords: ache; pharmacological agents; carboxylesterase inhibitors; cholinesterase carboxylesterase ... See more keywords
Marine Sponges and Bacteria as Challenging Sources of Enzyme Inhibitors for Pharmacological Applications
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DOI: 10.3390/md15060173
Abstract: Enzymes play key roles in different cellular processes, for example, in signal transduction, cell differentiation and proliferation, metabolic processes, DNA damage repair, apoptosis, and response to stress. A deregulation of enzymes has been considered one… read more here.
Keywords: sponges bacteria; pharmacological applications; bacteria challenging; enzyme inhibitors ... See more keywords