Adverse effects of proton pump inhibitors (PPIs) on Renal system using Data Mining Algorithms (DMAs).
Sign Up to like & getrecommendations! Published in 2023 at "Expert opinion on drug safety"
DOI: 10.1080/14740338.2023.2189698
Abstract: BACKGROUND : Various Adverse Drug Reactions (ADRs) are associated with Proton Pump Inhibitors (PPIs). However, the effects of PPIs on renal system are unclear so far. Thus, the main objective of the current study was… read more here.
Keywords: system; pump inhibitors; proton pump; inhibitors ppis ... See more keywords
Unintended effects of proton pump inhibitors (PPIs) in patients with glioblastoma (GBM): A double-edged sword
Sign Up to like & getrecommendations! Published in 2022 at "Neuro-Oncology Practice"
DOI: 10.1093/nop/npac035
Abstract: A vast literature demonstrates that aldehyde dehydrogenase-1A1 (ALDH1A1) mediates therapy resistance and is associated with poor prognosis across human cancers. In glioblastoma (GBM), ALDH1A1 expression above vs below the mean causes temozolomide and radiation resistance… read more here.
Keywords: pump inhibitors; proton pump; inhibitors ppis; glioblastoma gbm ... See more keywords
Impact of proton pump inhibitors (PPIs) on sunitinib (SU) pharmacokinetics (PK) and activity in GIST patients (pts).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.11538
Abstract: 11538Background: PPIs alter the PK of several oral drugs, either through a decrease in absorption due to higher GI tract pH, or the induction of efflux pumps such as ABCB1. The PK of SU is… read more here.
Keywords: pump inhibitors; inhibitors ppis; ppis sunitinib; sunitinib pharmacokinetics ... See more keywords