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Arginase Inhibitors: A Rational Approach Over One Century

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Published in 2017 at "Medicinal Research Reviews"

DOI: 10.1002/med.21419

Abstract: Arginase (EC 3.5.3.1) is the bimanganese enzyme that converts L‐arginine into ornithine and urea. This enzyme was discovered more than a century ago and early α‐amino acids were identified as weak inhibitors. It was only… read more here.

Keywords: arginase inhibitors; arginase; century; rational approach ... See more keywords