Histone deacetylase 8 (HDAC8) and its inhibitors with selectivity to other isoforms: An overview.
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DOI: 10.1016/j.ejmech.2018.12.039
Abstract: The histone deacetylases (HDACs) enzymes provided crucial role in transcriptional regulation of cells through deacetylation of nuclear histone proteins. Discoveries related to the HDAC8 enzyme activity signified the importance of HDAC8 isoform in cell proliferation,… read more here.
Keywords: inhibitors selectivity; hdac8 inhibitors; hdac8; histone deacetylase ... See more keywords
Recombinant Porcine 12-Lipoxygenase Catalytic Domain: Effect of Inhibitors, Selectivity of Substrates and Specificity of Oxidation Products of Linoleic Acid
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DOI: 10.3390/foods11070980
Abstract: Lipoxygenase (LOX) is a major endogenous enzyme for the enzymatic oxidation of lipids during meat storage and meat product manufacturing. In the present work, some characteristics, i.e., effects of inhibitors, selectivity of substrates and specificity… read more here.
Keywords: recombinant porcine; oxidation; inhibitors selectivity; lipoxygenase ... See more keywords