Drug-like Inhibitors of DC-SIGN Based on a Quinolone Scaffold.
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DOI: 10.1021/acsmedchemlett.2c00067
Abstract: DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin) is a pattern recognition receptor expressed on immune cells and involved in the recognition of carbohydrate signatures present on various pathogens, including HIV, Ebola, and SARS-CoV-2. Therefore, developing… read more here.
Keywords: inhibitors sign; drug like; quinolone scaffold; sign based ... See more keywords