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Published in 2017 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2017.07.016
Abstract: The recent successes of immune check point targeting therapies in treating cancer patients has driven a resurgence of interest in targeting these pathways in chronically infected patients. While still in early stages, basic and clinical…
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Keywords:
inhibitors therapies;
point inhibitors;
infectious diseases;
check point ... See more keywords
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Published in 2023 at "Epigenomics"
DOI: 10.2217/epi-2022-0320
Abstract: EZH2 is an epigenetic regulator that methylates lysine 27 on histone H3 (H3K27) and is closely related to the development and metastasis of tumors. It often shows gain-of-function mutations in hematological tumors, while it is…
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Keywords:
therapies solid;
combining ezh2;
tumors choices;
inhibitors therapies ... See more keywords