EZH2 Inhibitors: The Unpacking Revolution
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DOI: 10.1158/0008-5472.can-21-4311
Abstract: The methylation of lysine 27 on histone H3 (H3K27me3) is a chromatin mark associated with nucleosome condensation and gene expression silencing. EZH2 is a lysine methyltransferase that catalyzes H3K27me3. In this issue of Cancer Research,… read more here.
Keywords: inhibitors unpacking; ezh2 inhibitors; unpacking revolution;