Exploring biological efficacy of coumarin clubbed thiazolo[3,2-b][1,2,4]triazoles as efficient inhibitors of urease: A biochemical and in silico approach.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.09.105
Abstract: Combating several pathological conditions associated with ureolytic enzyme (urease) remains a formidable challenge because of the lack of effective and safe drug therapies. In this regard, the development of potent inhibitors of urease could be… read more here.
Keywords: exploring biological; inhibitors urease; biological efficacy; coumarin clubbed ... See more keywords
An overview: metal-based inhibitors of urease.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of enzyme inhibition and medicinal chemistry"
DOI: 10.1080/14756366.2022.2150182
Abstract: Urease is a kind of nickel-dependent metalloenzyme, which exists in the biological world widely, and can catalyse the hydrolysis of urea into ammonia and carbon dioxide to provide a nitrogen source for organisms. Urease has… read more here.
Keywords: inhibition; inhibitors urease; metal based; overview metal ... See more keywords