Mechanisms of inhibitory action of TRK-130 (Naltalimide), a μ-opioid receptor partial agonist, on the micturition reflex
Sign Up to like & getrecommendations! Published in 2017 at "International Urology and Nephrology"
DOI: 10.1007/s11255-017-1509-y
Abstract: PurposeTo clarify the mechanism of inhibitory action of TRK-130 (Naltalimide), a unique µ-opioid receptor partial agonist, on the micturition reflex.MethodsThe effect of TRK-130 on isovolumetric rhythmic bladder contractions (RBCs) was examined in guinea pigs, the… read more here.
Keywords: action trk; trk 130; bladder; micturition reflex ... See more keywords
Exploration of inhibitory action of Azo imidazole derivatives against COVID-19 main protease (Mpro): A computational study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.129178
Abstract: Four novel ionic liquid tagged azo-azomethine derivatives (L1-L4) have been prepared by the condensation reaction of azo-coupled ortho-vaniline precursor with amino functionalised imidazole derivative and the synthesized derivatives (L1-L4) have been characterized by different analytical… read more here.
Keywords: protease; inhibitory action; main protease; kcal mole ... See more keywords
Docking Assisted Prediction and Biological Evaluation of Sideritis L. Components with PTP1b Inhibitory Action and Probable Anti-Diabetic Properties.
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DOI: 10.2174/1568026619666190219104430
Abstract: BACKGROUND The main characteristic of Diabetes type II is the impaired activation of intracellular mechanisms triggered by the action of insulin. PTP1b is a Protein Tyrosine Phosphatase that dephosphorylates insulin receptor causing its desensitization. Since… read more here.
Keywords: sideritis components; inhibitory action; ptp1b inhibitory; action ... See more keywords
Synergy of the Inhibitory Action of Polyphenols Plus Vitamin C on Amyloid Fibril Formation: Case Study of Human Stefin B
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DOI: 10.3390/antiox10091471
Abstract: In order to study how polyphenols and vitamin C (vitC) together affect protein aggregation to amyloid fibrils, we performed similar in vitro studies as before using stefin B as a model and a potentially amyloid-forming… read more here.
Keywords: synergy inhibitory; action polyphenols; plus vitamin; study ... See more keywords