Green synthesis of silver and gold nanoparticles using Crataegus oxyacantha extract and their urease inhibitory activities.
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2018
Abstract: This study reports the green synthesis and urease inhibitory activities of Ag and Au nanoparticles (NPs) using Crataegus oxyacantha extract. The as-synthesized NPs were characterized by UV-Visible, FT-IR spectroscopy, Atomic Force Microscopy (AFM) and Scanning… read more here.
Keywords: green synthesis; urease inhibitory; inhibitory activities; microscopy ... See more keywords
α-Amylase and α-glucosidase inhibitory activities of the herbs of Artemisia dracunculus L. and its active constituents
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DOI: 10.1007/s00044-017-2014-7
Abstract: A new phenylpropanoid named 4-(1′,1′,2′,2′-tetramethylpropyl)-1,2-benzenediol (1) with a known phenylpropanoid: 3-(p-methoxyphenyl)-1,2-propanediol (2), a coumarin: herniarin (3), and a flavonol glycoside: rutin (4) were isolated from the aerial parts of Artemisia dracunculus L. Their structures were… read more here.
Keywords: activities herbs; inhibitory activities; artemisia dracunculus; inhibitory ... See more keywords
Inhibitory activities of tree bark extracts against AGEs formation and their correlation with phenolic components
Sign Up to like & getrecommendations! Published in 2018 at "Wood Science and Technology"
DOI: 10.1007/s00226-018-1002-5
Abstract: Advanced glycation end-products (AGEs) are one of the pivotal factors that cause a variety of diabetes complications. To explore a new class of natural resources that can prevent AGEs formation, the inhibitory activities of tree… read more here.
Keywords: bark; ages formation; inhibitory activities; tree bark ... See more keywords
Undersampling: case studies of flaviviral inhibitory activities
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Computer-Aided Molecular Design"
DOI: 10.1007/s10822-019-00255-3
Abstract: Imbalanced datasets, comprising of more inactive compounds relative to the active ones, are a common challenge in ligand-based model building workflows for drug discovery. This is particularly true for neglected tropical diseases since efforts to… read more here.
Keywords: zikv inhibitory; wnv zikv; inhibitory activities; performance ... See more keywords
Inhibitory activities of kukoamines A and B from Lycii Cortex on amyloid aggregation related to Alzheimer’s disease and type 2 diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-019-01337-0
Abstract: Alzheimer’s diseases (AD) and type 2 diabetes (T2D) are two age-related diseases characterized by amyloid fibrillogenesis. Prevention of amyloid aggregation is a promising therapeutic strategy for AD and T2D. Two spermine alkaloids, kukoamines A and B, isolated… read more here.
Keywords: aggregation; activities kukoamines; inhibitory activities; type diabetes ... See more keywords
Metabolites with phytopathogenic fungi inhibitory activities from the mangrove endophytic fungus Botryosphaeria ramose.
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DOI: 10.1016/j.bioorg.2020.104300
Abstract: To check whether the endophytic fungus from the host plant could produce novel bioactive metabolites induced by the host-derived chemical components, a strategy called "Induction of Endophyte Metabolism by Adding Host Components" (IEMAHC) was put… read more here.
Keywords: endophytic fungus; fungus; inhibitory activities; fungus botryosphaeria ... See more keywords
Carbazole alkaloids from the fruits of Clausena anisum-olens with potential PTP1B and α-glucosidase inhibitory activities.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104775
Abstract: The phytochemical investigation on the fruits of Clausena anisum-olens led to the isolation of 18 carbazole alkaloids (1-18), containing three new ones, clausenanisines A-C (1-3), and three new naturally occurring carbazole alkaloids, clausenanisines D-F (4-6),… read more here.
Keywords: inhibitory activities; ptp1b glucosidase; anisum olens; carbazole alkaloids ... See more keywords
Two new phenylethanoid glycosides from Ginkgo biloba leaves and their tyrosinase inhibitory activities.
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DOI: 10.1016/j.carres.2020.108059
Abstract: Two undescribed phenylethanoid glycosides, Ginkgoside C (1) and D (2), together with ten known glycosides (3-12) were isolated from Ginkgo biloba leaves. Their structures were characterized by physical data analyses such as NMR, HRESIMS, as… read more here.
Keywords: ginkgo biloba; inhibitory activities; tyrosinase inhibitory; biloba leaves ... See more keywords
Discovery of aliphatic-chain hydroxamates containing indole derivatives with potent class I histone deacetylase inhibitory activities.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.11.092
Abstract: Histone deacetylase (HDAC) is a validated drug target for various diseases. This study combined indole recognition cap with SAHA, an FDA-approved HDAC inhibitor used to treat cutaneous T-cell lymphoma (CTCL). The structure activity relationship of… read more here.
Keywords: chain; activity; inhibitory activities; histone deacetylase ... See more keywords
Design, synthesis and biological evaluation of novel naphthoquinone derivatives as IDO1 inhibitors.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.08.013
Abstract: Indoleamine 2,3-dioxygenase 1 (IDO1) mediated kynurenine pathway of tryptophan degradation is identified as an appealing and novel target in immunotherapy for the treatment of cancer. In this study, a novel series of naphthoquinone derivatives were… read more here.
Keywords: design synthesis; biological evaluation; inhibitory activities; naphthoquinone derivatives ... See more keywords
Phytochemical profile and biological activities of Anatolian Plantain (Plantago anatolica)
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DOI: 10.1016/j.fbio.2020.100658
Abstract: Abstract The phytochemical profile and potential biological activities of Plantago anatolica Tutel & R. Mill., a traditional endemic food plant of Eastern Anatolia, Turkey, were studied. The study included analysis of phytochemical and mineral compositions… read more here.
Keywords: ic50 respectively; biological activities; inhibitory activities; plantago anatolica ... See more keywords