The RAG-2 Inhibitory Domain Gates Accessibility of the V(D)J Recombinase to Chromatin
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DOI: 10.1128/mcb.00159-18
Abstract: Accessibility of antigen receptor loci to RAG is correlated with the presence of H3K4me3, which binds to a plant homeodomain (PHD) in the RAG-2 subunit and promotes V(D)J recombination. A point mutation in the PHD,… read more here.
Keywords: recombination; h3k4me3; inhibitory domain; rag ... See more keywords