Erbb4 Deletion From Inhibitory Interneurons Causes Psychosis-Relevant Neuroimaging Phenotypes
Sign Up to like & getrecommendations! Published in 2022 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbac192
Abstract: Abstract Background and Hypothesis Converging lines of evidence suggest that dysfunction of cortical GABAergic inhibitory interneurons is a core feature of psychosis. This dysfunction is thought to underlie neuroimaging abnormalities commonly found in patients with… read more here.
Keywords: inhibitory interneuron; density; deletion; psychosis ... See more keywords
Delineating selective vulnerability of inhibitory interneurons in Alpers' syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12833
Abstract: Alpers' syndrome is a severe neurodegenerative disease typically caused by bi‐allelic variants in the mitochondrial DNA (mtDNA) polymerase gene, POLG, leading to mtDNA depletion. Intractable epilepsy, often with an occipital focus, and extensive neurodegeneration are… read more here.
Keywords: delineating selective; vulnerability inhibitory; inhibitory; alpers syndrome ... See more keywords
State transitions through inhibitory interneurons in a cortical network model.
Sign Up to like & getrecommendations! Published in 2021 at "PLoS computational biology"
DOI: 10.1371/journal.pcbi.1009521
Abstract: Inhibitory interneurons shape the spiking characteristics and computational properties of cortical networks. Interneuron subtypes can precisely regulate cortical function but the roles of interneuron subtypes for promoting different regimes of cortical activity remains unclear. Therefore,… read more here.
Keywords: fast spiking; inhibitory interneurons; state; network ... See more keywords
The Role of Inhibitory Interneurons in Circuit Assembly and Refinement Across Sensory Cortices
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2022.866999
Abstract: Sensory information is transduced into electrical signals in the periphery by specialized sensory organs, which relay this information to the thalamus and subsequently to cortical primary sensory areas. In the cortex, microcircuits constituted by interconnected… read more here.
Keywords: sensory cortices; circuit; role inhibitory; across sensory ... See more keywords
Spinal inhibitory interneurons: regulators of coordination during locomotor activity
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2023.1167836
Abstract: Since the early 1900’s it has been known that a neural network, situated entirely within the spinal cord, is capable of generating the movements required for coordinated locomotion in limbed vertebrates. Due the number of… read more here.
Keywords: locomotor activity; locomotor; spinal cord; spinal inhibitory ... See more keywords
Peripheral Nerve Injury Induces Changes in the Activity of Inhibitory Interneurons as Visualized in Transgenic GAD1-GCaMP6s Rats
Sign Up to like & getrecommendations! Published in 2022 at "Biosensors"
DOI: 10.3390/bios12060383
Abstract: Peripheral nerve injury induces cortical remapping that can lead to sensory complications. There is evidence that inhibitory interneurons play a role in this process, but the exact mechanism remains unclear. Glutamate decarboxylase-1 (GAD1) is a… read more here.
Keywords: peripheral nerve; gad1; activity; injury ... See more keywords
Three rules govern thalamocortical connectivity of fast-spike inhibitory interneurons in the visual cortex
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.60102
Abstract: Some cortical neurons receive highly selective thalamocortical (TC) input, but others do not. Here, we examine connectivity of single thalamic neurons (lateral geniculate nucleus, LGN) onto putative fast-spike inhibitory interneurons in layer 4 of rabbit… read more here.
Keywords: spike inhibitory; inhibitory interneurons; visual cortex; connectivity ... See more keywords